作者:LIU; Tian-long; WANG; Wen-jun; DING; Yi; WEN; Ai-dong; ZHANG; Ru-xue 期刊:《中国药理学与毒理学》 2019年第09期
OBJECTIVE To investigate the neuroprotective effects and exact mechanisms of myrrh extract following cerebral ischemic stroke.METHODS Male rats were randomly divided into three groups:sham group,middle cerebral artery occlusion(MCAO)group and myrrh group.Morphological changes were assessed after 7 d of myrrh treatment.Microarray analysis with circulating mRNA was performed to identify differenti...
作者:MA; Hui-xia; HOU; Fan; ZHANG; Zheng-jun; CHEN; Ai-ling; ZHU; Ya-fei; Li; Ting-ting; ZHANG; Xin-hui; ZHAO; Qi-peng 期刊:《中国药理学与毒理学》 2019年第09期
OBJECTIVE TO investigate the neural protection of dehydrocostus lactone(DHL)against neuronal injury induced by oxygen and glucose deprivation/reperfusion(OGD/R)in differentiated PC12 cells.METHODS We used a cellular model of 2 h of OGD and 24 h of reperfusion to mimic cerebral ischemia-reperfusion injury.Cell viability was used to reflect the degree of OGD/R-induced injury.Cells were treated wit...
作者:徐艳; 徐志广; 章小慧; 陈华彬; 许旋; 刘海洋 期刊:《结构化学》 2019年第11期
The effects of axial ligand on the oxygen atom transfer(OAT)reaction from 5,10,15-tris(pentafluorophenyl)corrole((tpfc)MnVO)to dimethyl sulfide(DMS)have been investigated by density functional theory(DFT)calculations.Imidazole(Im),4-methylimidazole(4-MI)and pyridine(Py)were selected as the axial ligands.The results revealed that the axial ligand can form coordinate bond with(tpfc)MnVO in the tra...
Are you ready for a trip through our solar system?Then jump into your imaginary spaceship.Buckle your seatbelt.Turn on the oxygen supply.Give the signal to blast off.We leave our planet Earth at the speed of light.
据说,高尔夫(GOLF)是由绿色(Gteen)、氧气(Oxygen)、阳光(Light)和友谊(Friendship)4个英文单词的首字母组成的。我不知道最初的翻译者是谁,如果是我,我认为译作"高而富"更为恰切。因为它实在是一项彻头彻尾的贵族运动,只要和它沾上边,就得大把大把的银子往里扔。建一个高尔夫球场,需占地1000亩,其建设费达3亿元左右,仅年维修费就要3000万元。在我们这样一个刚刚解决温饱问题的国家,这是能把没见过世面的老百姓吓傻了的天文数字。...
作者:赵玉芝; 李军 期刊:《中医临床研究》 2014年第12期
目的:探讨高压氧(HBO)的应用范围,观察高压氧在精神疾病中的作用及疗效。方法:抑郁症患者134例随机分为研究组65例和对照组69例,两组均常规应用抗抑郁药物盐酸帕罗西汀片、米氮平片及中成药健脑补肾丸,研究组同时加用高压氧治疗。并将两组结果进行比较。结果:治疗2周后研究组和对照组药量分别为20㎎、15㎎和30㎎、30㎎时,即出现明显差异。四周后两组药量分别为20㎎、15㎎、和30㎎、37.5㎎,两组显效率和有效率经统计学处...
作者:TOMINAGA; Chiaki; HIKOSOU; Dailo; OSAKA; Issey; KAWASAK; Hideya 期刊:《物理化学学报》 2018年第07期
作者:GAO; Xiao-mei; PAN; Ying-min; CHEN; Yi-ping 期刊:《光谱学与光谱分析》 2018年第S1期
In this paper,the synthesis of a novel polyoxovanadiumborate Cd0.75 Na2 Ni0.5 [V12 B18 O50.5(OH)9.5]·27.5 H2 O by hydrothermal method.The compound consists of metal M(Cd,Na,Ni)and V12 B18 O60 cluster units connected through the M-O bond to form a three-dimensional structure.We performed a series of characterizations of Compound 1 of our team and tested its fluorescence properties at the same...
作者:SHI; Kunpeng; DONG; Shuanglin; ZHOU; Yangen; GAO; Qinfeng; LI; Li; ZHANG; Meizhao; SUN; Dajiang 期刊:《中国海洋大学学报·自然科学版》 2018年第06期
This study was conducted to evaluate the critical thermal maximum(CTMax),the routine metabolism rate(MO2)and the limiting oxygen saturation(LOS)of three salmonids with four different body weights ranging from 16 g to 131 g.The CTMax was estimated at three different heating rates including 0.5℃min^-1,1℃h^-1 and 2℃d^-1.Results showed that the CTMax of maple trout(Oncorhynchus mykiss)was the hig...
作者:XU; Fan; LYU; Chun; DENG; Yan; LIU; Yuan-gui; GONG; Qi-hai; SHI; Jing-shan; GAO; Jian-mei 期刊:《中国药理学与毒理学》 2018年第09期
OBJECTIVE To explore the effects and mechanism of icariside Ⅱ(ICS Ⅱ),a pharmacologically active compound derived from herbal Epimedii with previous study-proved phosphodiesterase 5(PDE5) inhibitors,was investigated in vivo using a middle cerebral artery occlusion/reperfusion(MCAO/R) model in rats and in vitro using an oxygen-glucose deprivation/reperfusion(OGD/R) model in primary hippocampal n...
作者:ZHENG; Yan-rong; ZHANG; Xiang-nan; CHEN; Zhong 期刊:《中国药理学与毒理学》 2018年第09期
Cerebral ischemia remains the top causes of mortality and disability worldwide. The pathological mechanisms underlying ischemic brain injury are not fully illustrated. Cerebral ischemia induces massive mitochondrial damage, which are cleared by mitochondrial autophagy (mitophagy). Our previous studies indicated mitophagy is critical for neuronal survival after ischemic injury, thus raise the con...
作者:岳建伟; 师希雄; 孙金龙; 余群力; 朱琪 期刊:《食品与发酵工业》 2019年第02期
宰后成熟是提高肉品质的有效途径之一,为了改善肉品质,活性氧(reactive oxygen species,ROS)介导的氧化应激已成为国内外学者的研究热点,但ROS介导的氧化应激的研究主要集中在医学领域。通过综述ROS介导的细胞死亡方式(凋亡、自噬与坏死)可能与肉品质之间的关系,以及ROS对肉色泽、风味、嫩度的影响,来阐述ROS介导的氧化应激可能在宰后成熟过程中对肉品质的影响。
作者:范红伟; 吴铜伟; 刘媛媛; 卫河转; 安胜利; 贾桂霄 期刊:《结构化学》 2019年第06期
Influence of doping and oxygen vacancy concentrations on oxygen ion or oxygen vacancy(V)migration energies of SmxCe1-xO2-δ(x=0.0625,0.125,0.25 andδ=0.0625,0.125)systems using a GGA+U method are studied.Calculated results show that advantage migration types change from V→O2-to O2-→as x andδincrease.For V→O2-migrations of the Sm0.0625Ce0.9375O1.9375 and Sm0.125Ce0.875O1.9375 systems,electrostat...
作者:蔡阳扬; 岑竞仪; 欧林坚; 吕颂辉 期刊:《暨南大学学报·自然科学与医学版》 2014年第03期
在2012年夏季(8月)和秋季(11月)对珠江口海域进行化学需氧量(COD)、溶解氧(DO)和氮磷营养盐调查分析,并研究了其分布特征,采用富营养化指数法和潜在性富营养化法对珠江口水体营养化状况进行了分析和评价.结果显示,珠江口海域COD质量浓度较低,夏季平均值为1.85 mg/L,秋季为1.10 mg/L;DO质量浓度较高,夏季平均值为6.95 mg/L,秋季为7.63 mg/L;无机氮污染严重,平均质量浓度夏季为0.85 mg/L,秋季为0.79 mg/L,总体...
作者:CHEN; Zuxing; ZENG; Zhigang; WANG; Xiaoyuan; ZHANG; Yuxiang; YIN; Xuebo; CHEN; Shuai; MA; Yao; LI; Xiaohui; QI; Hanyan 期刊:《中国海洋大学学报·自然科学版》 2017年第06期
To reveal the petrogenesis of rhyolite from the southwestern Okinawa Trough, the mineral chemistry of plagioclase,orthopyroxene, amphibole, quartz and Fe-Ti oxide phenocrysts were analyzed using an electron microprobe, and in suit Sr and Ba contents of plagioclase analysed by LA-ICPMS were chosen for fingerprinting plagioclases of different provenances. Results indicate an overall homogeneous co...
作者:谷瑞环; 孙贻娟; 冯云; 孙晓溪 期刊:《中国优生与遗传》 2017年第05期
目的探索玻璃化冷冻人卵子中ROS的产生和修复。方法收集本中心ICSI周期中未成熟卵子MI,体外培养成熟至MII后,随机分为3组:A组:新鲜卵子;B组:玻璃化冷冻复苏后培养0h;C:玻璃化冷冻复苏后培养2 h;D组:玻璃化冷冻复苏后培养4h。利用2′7′-二氯二氢荧光素二乙酯检测以上3组卵子的ROS产生,然后用t检验进行统计分析。结果本实验共收集卵子数:A组:45枚;B组:52枚;C组:49枚;D组:50枚。卵子经染色及统计分析后,A、B、D 3组卵子的R...
作者:Felix; Distelmaier; Henk-Jan; Visch; Jan; A.M.Smeitink; Ertan; Mayatepek; Werner; J.H.Koopman; Peter; H.G.M.Willems 期刊:《世界最新医学信息文摘》 2016年第11期
Malfunction of mitochondrial complex I caused by nuclear gene mutations causes early-onset neurodegenerative diseases. Previous work using cultured fibroblasts of complex-I-deficient patients revealed elevated levels of reactive oxygen species(ros) and reductions in both total Ca2+ content of the endoplasmic reticulum(ERCa) and bradykinin(Bk)-induced increases in cytosolic and mitochondrial ...
作者:YAO; Haidong; FAN; Ruifeng; ZHAO; Xia; ZHANG; Ziwei; XU; Shiwen 期刊: 2015年第Z1期
Ca2+ leak induces the mitochondria or sarco/endoplasmic reticulum(SR/ER)related cell death.In the present study,we examined the contribution of SR-released Ca2+ through ryanodine receptors(RyR) to the muscular injuries in Selenoprotein W(Selw) silencing myoblast model.The results showed that Selw deficiency induced Ca2+release from SR,which led the accumulation of Ca2+ in mitochondria as w...