作者:Editorial; Board; of; Nursing; of; Integrated; Traditional; Chinese; and; Western; Medicine 期刊: 2019年第10期
ABSTRACT:Knee osteoarthritis(KOA),a complicated peripheral joint disorder,can be caused by non-modifiable and modifiable risk factors.At present,the treatment for osteoarthritis is mainly to manage symptoms and improve quality of life.Although some patients with osteoarthritis may choose pharmacological agents for pain relief,it has been confirmed that a variety of preparations and doses of phar...
作者:HE; Bao-kun 期刊:《中国药理学与毒理学》 2019年第09期
OBJECTIVE Dysregulation of circadian rhythms is associated with metabolic dysfunction,yet it is unclear whether enhancing clock function by small molecules can ameliorate metabolic disorders.METHODS We used an unbiased chemical screen in fibroblasts expressing PER2::Luc to identify the Clock amplitude-Enhancing Small Mole⁃cule.In diet-induced obese mice and DB/DB mutant mice,we evaluated the ef...
作者:LI; Yue; Michael; ESTOCKTON; Brian; EEISINGER; ZHAO; Ying-hua; Jessica; LMILLER; Ismat; BHUIYAN; GAO; Yu; WU; Zhi-ping; PENG; Jun-min; ZHAO; Xin-yu 期刊:《中国药理学与毒理学》 2019年第09期
Fragile X syndrome(FXS)is the most prevalent inherited intellectual disability,resulting from a loss of fragile X mental retardation protein(FMRP).Patients with FXS suffer lifelong cognitive disabilities,but the function of FMRP in the adult brain and the mechanism underlying age-related cognitive decline in FXS is not fully understood.Here,we report that a loss of FMRP results in increased prot...
作者:李粲 期刊:《中国医学文摘·耳鼻咽喉科学》 2019年第02期
Objective To analyze the clinical characteristics ofantiphospholipid syndrome (APS) patients with chronicthromboembolic pulmonary hypertension ( CTEPH ).Methods A total of 22 APS patients with CTEPH wereenrolled in our study,who were admitted in PekingUnion Medical College Hospital from January 2012 toAugust 2018. Diagnoses were confirmed by computed to-mographic pulmonary angiography (CTPA),or ...
作者:蒋蓉 期刊:《中国医学文摘·耳鼻咽喉科学》 2019年第02期
Objective To investigate the incidence situation ofmetabolic syndrome (MS) in patients with continuousambulatory peritoneal dialysis (CAPD),and analyze thecorrelation between MS and prognosis of patients. MethodsThe patients who received peritoneal dialysis fromJune 1,2002 to April 30,2018 and followed up regularlywere divided into MS group and non-MS group accordingto the diagnostic criteria of...
作者:王树水; 李虹; 区曦; 曾少颖; 李渝芬 期刊:《中华心律失常学》 2005年第05期
长QT综合征(long QT syndrome,LQTS)是一类可能发生恶性心律失常的综合征,分为先天性及获得性两大类型.
随着心律失常研究的深入,致病基因不断被发现,基因型与临床表型的复杂关系正在逐步被认识。与长QT综合征、Brugada综合征一样,近几年来对钙离子通道基因异常引起的心律失常如儿茶酚胺性多形室速(catecholaminergic polymorphic ventficular tachycardia,CPVT)或家属性多形室速(family polymorphic ventricular tachycardia,FPVT)、致心律失常性右心室心肌病2型(arrhythmogenic right ventricular caldiomyopathy type2(...
作者:裘洁; 朱雄凯; 李建华 期刊:《预防医学》 2006年第09期
在婴幼儿体外循环(cardiopulmonary bypass,CPB)手术期间,CPB诱发全身炎症反应综合症(systemic inflammatory response syndrome,SIRS)可以引起组织损伤和器官功能紊乱,引发感染、败血症、急性呼吸窘迫症及多器官功能不全等严重并发症。而传统的炎症监测指标缺乏敏感性和时效性,因此,寻找敏感、有效的监测指标,早期认定炎症反应程度,及时进行干预,具有现实的临床意义。本实验探讨婴幼儿体外循环过程对血清降钙索原(P...
艾滋病是获得性免疫缺陷综合征(acquired immunodeficiency syndrome,AIDS)的简称,是由人免疫缺陷病毒(human immunodeficicy virus,HIV)引起的以免疫系统损害和感染为主要特征的一组综合征.20世纪80年代艾滋病被称为"世纪瘟疫",90年代后期由于高效联合抗病毒治疗的广泛应用,大大降低了艾滋病的发病率和死亡率;因此,目前艾滋病被认为是一种通过抗病毒治疗可以控制病情进展并能够长期生存的慢性传染病.
作者: 期刊: 2019年第06期
Hemorrhoids, one of the common anorectal diseases, are characterized by painless rectal bleeding during defecation with or without prolapsed anal tissues. It is universally recognized that the occurrence of hemorrhoids is not only related to the conditions that increase intra-abdominal pressure, but also to the aging, obesity, depressive mood, pregnancy, and so on. The treatment for hemorrhoids ...
作者: 期刊: 2019年第05期
he incidence and mortality of colorectal cancer(CRC)are on the rise in China and rank the fifth in all malignant cancers,which may result from the increasingly aging population and unhealthy lifestyles.At present,the major treatment methods for CRC include laparoscopic surgery,radiotherapy and neoadjuvant and palliative chemotherapies,but they all have the limited impact on cure rates and long-t...
作者:Editorial; Board; of; Nursing; of; Integrated; Traditional; Chinese; and; Western; Medicine 期刊: 2019年第07期
Osteoarthritis(OA)is one of the leading causes of disability worldwide,and its prevalence increases with age.With the aggravated aging of population,OA has negatively impacted the people's physical and mental well-being.For the past few years,Traditional Chinese Medicine(TCM)has shown its predominant advantages in the treatment of OA.It can alleviate pain and improve clinical symptoms in patient...
作者:Editorial; Board; of; Nursing; of; Integrated; Traditional; Chinese; and; Western; Medicine 期刊: 2018年第11期
Herpes zoster is a viral infection caused by the reactivation of endogenous latent varicella zoster virus resulting in varicella, characterized by pain and vesicles in the restricted dermatomal distribution that occurs along the nerves with dormant virus. Postherpetic neuralgia (PHN) is the most common sequela of herpes zoster, occurs or persists after the rash has resolved. It is currently reco...
作者:DU; Furong 期刊: 2018年第08期
作者:张大鹏; 杨新春; 王乐丰 期刊:《中国介入心脏病学》 2005年第06期
经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)是急性冠状动脉综合征(acute coronary syndrome,ACS)再灌注治疗的主要手段之一,但是不少患者术后会出现慢血流或无再流现象.造成该现象的原因较复杂,其机制包括再灌注损伤,微血管痉挛,血小板激活/聚集,内皮细胞肿胀,管壁水肿以及由血栓、破裂斑块的碎片所造成的远端微血管栓塞等[1],而后者正是PCI操作过程中并不少见的一种情况,这使得罪犯血管虽然能够再通,但达不到...
作者:孙琳; 刘爱芬; 任建民; 尚伟; 周庆博; 许顺良 期刊:《中华老年医学》 2005年第11期
不宁腿综合征(restless legs syndrome, RLS)是指阵发性双下肢深部难以忍受的不适感,患者不能保持安静,强迫活动后才能暂时缓解的一种综合征.健康人群患病率为5%~15%,并随年龄增长而上升,国外报道在65岁以上老年人中占10%~28%[1].我们对55例RLS老年患者的情况进行了回顾性分析.
作者:贺颖; 郑红; 连建华; 齐华; 许培钦; 林国领; 董子明 期刊:《中华血液学》 2005年第09期
布-加综合征(Budd-Chiari syndrome,B-CS)是指肝静脉和(或)下腔静脉流出道受阻引起的门静脉高压和(或)下腔静脉高压综合征.流出道的阻塞多由于肝静脉和(或)下腔静脉血栓形成所致,故导致血栓形成的各种因素就成为B-CS病因学研究的热点[1].
作者:戴兵; 刘亚伟; 梅长林 期刊:《临床肾脏病》 2005年第06期
溶血性尿毒症综合征(hemo1ytic uremic syndrome,HUS),于1955年首先由Gasser报道。它是一种以微血管性溶血性贫血、血小板减少和急性肾功能不全为临床特点的综合征。本文就近年来HUS的分类、病因及发病机制研究进展作一介绍。
作者:闵晓霞; 陈静; 吴德全 期刊:《现代临床医学》 2006年第04期
正常甲状腺病态综合征(Euthyriod Sick Syndrome:ESS)是L995年由Engstrom等人在“低三碘甲状腺原氨酸(T3)综合征”的基础上首次提出的一个新概念,它是指在一些严重的急性和(或)慢性非甲状腺疾病(NTI)患者中血清甲状腺激素降低,而促甲状腺激素(TSH)正常,临床上无甲状腺功能减退表现的一组综合征。本文通过检测284例NTI患者的血清甲状腺激素浓度,对甲状腺激素在NTI患者中所出现的变化及其临床意义进行了研究,报告如...
作者:李悦; 崔振泽(审校); 陈爱勇 期刊:《中国妇幼保健》 2006年第12期
近几年来,随着睡眠医学的不断发展,人们越来越认识到睡眠障碍是影响儿童生长发育的重要因素。而儿童最常见、最严重的睡眠问题是阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome OSAS),它对儿童身心健康造成的危害是严重而隐袭的。OSAS可导致儿童白天过度睡眠、行为问题、睡眠时觉醒的混乱、中枢认知能力的下降等,长期发作可导致高血压、生长发育落后、肺动脉高压、甚至突然死亡。因此充分认识和研究OSAS对儿童...