《合成化学》杂志2004年第Z1期期刊目录-发表之家

Chemistry of 1,16-Dihydroxytetraphenylene and 2,3,9,10-Tetrakis(trimethylsilyl) pentacene

作者：Wen; Jian-Feng; Chan; Siu-Hin; Wong; Henry; N.C. 刊期：2004年第Z1期

Recently, four tetraphenylenols, as well as several non-substituted and substituted 2,3,9,10-tetrakis(trimethylsilyl)pentacenes were realized in our laboratories. In this presentation, the synthesis, hydrogen bonding properties, and chiral recognition studies of (S)- 1,16-dihydroxytetraphenylene (1) and its (R)-enant...
New Chiral Ligands: From Fundamental Research to Potential Industrial Applications

作者：Albert; S.; C.; Chan 刊期：2004年第Z1期

Asymmetric catalysis is one of the most extensively studied areas in chemistry over the past three decades. In this presentation we will discuss the new advancements in the design,synthesis, and application of chiral ligands used for catalytic reactions in our laboratory. Particular emphasis will be placed on new, hi...
Studies on Atropo-Enantioselective Synthesis of the Natural Chiral Axial Biaryls

作者：LIN; Guo-Qiang 刊期：2004年第Z1期

Ary-aryl bond formation plays an important role in modem organic synthesis. These bonds are very of ten occurred in natural products such as alkaloids as well as in numerous biologically active parts of pharmaceutical and agrochemical specialties. In addition, they are also the scaffolds of some of the most efficient...
Approaches for Making High Performance Polymer Materials from Commodity Polymers

作者：Xu; Xi 刊期：2004年第Z1期

A brief surrey of ongoing research work done for improving and enhancing the properties of commodity polymers by the author and author's colleagues is given in this paper. A series of high performance polymers and polymer nanomaterials were successfully prepared through irradiation and stress-induced reactions of pol...
Skeletal Amorphous Nickel Based Alloy Catalysts and Magnetically Stabilized Bed Hydrogenation Technology

作者：Min; Enze 刊期：2004年第Z1期

Looking toward 21 century, smaller, cleaner and more energy-efficient technology will be an important trend in the development of chemical industry. In light of the new process requirements,a number of technology breakthroughs have occurred. One of these discoveries, the magnetically stabilized bed (MSB), has been pr...
High Throughput and High Speed Organic Synthesis in Drug Discovery: An Integration of Chemistry and Technology

作者：Li; Chen 刊期：2004年第Z1期

Drug discovery is a complicated process that involves multiple synthetic chemistry tasks.Among them, lead generation and optimization is the core business in the discovery research.During the stage of lead generation, a large library of many thousands individual compounds will be screened against a biological target ...
High Nonlinear Optic Activity Chromophore- Design and Synthesis

作者：He; Mingqian; Thomas; M.; Leslie 刊期：2004年第Z1期

Chromophores are the center piece of second order nonlinear optical (NLO) materials.The common chromophore consists of a Donor-Bridge-Acceptor structure. Donors and acceptors are connected by a bridge and together they make a fully conjugated system. Based on our previously synthesized novelacceptors [1], we have syn...
Novel Oxindoles as Potent Anti-HIV Agents

作者：HE; Yun; Jiang; Tao; David; Ellis; Beth; Anaclerio; Kelli; L.; Kuhen; Karen; Wolff; Yin; Hong; Kimberly; Bieza; Badry; Bursulaya; Tove; Tuntland; Perry; Gordon; Zhang; Kanyin; Jeremy; Caldwell 刊期：2004年第Z1期

Non-nucleoside reverse transcriptase inhibitors (NNRTI's) are a major component of the current therapy for AIDS. However, in recent years, significant resistance has been generated against the marketed NNRTI's (nevirapine, delavirdine and efavirenz) due to viral mutations. New NNRTI's are needed to overcome the incre...
Pharmaceutical Industry Oriented Homogeneous Catalysis

作者：Zhang; Xumu 刊期：2004年第Z1期

Chiral therapeutics already makes up over one-third of pharmaceutical drugs currently sold worldwide. This is a growing industry with global chiral drug sales for 2002 increasing by 12%to $160 billion (Technology Catalysts International) of a total drug market of $410bn. The increasing demand to produce enantiomerica...
Synthesis and Characterization of ZnO Nanowires

作者：Huang; Michael; Hsuan-Yi; Mao; Samuel; Henning; Feick; Yan; Haoquan; Wu; Yiying; Hennes; Kind; Richard; Russo; Eicke; Weber; Yang; Peidong 刊期：2004年第Z1期

Zinc oxide is a wide bandgap (3.37 eV) semiconductor with a hexagonal wurtzite crystal structure. ZnO prepared in nanowire form may be used as a nanosized ultraviolet light-emitting source. In this study, ZnO nanowires were prepared by vapor-phase transport of Zn vapor onto gold-coated silicon substrates in a tube fu...
Bisarylmaleimides & the Corresponding Indolocarbazoles as Kinase Inhibitors

作者：Zhu; Guoxin; Scott; E.; Conner; Zhou; Xun; Chuan; Shih; Li; Tiechao; Harold; B.; Brooks; Eileen; Considine; Jack; A.; Dempsey; Margaret; M.; Faul; Cathy; Ogg; Bharvin; Patel; Richard; M.; Schultz; Charles; D.; Spencer; Beverly; Teicher; Scou; A.; Watkins 刊期：2004年第Z1期

Cyclin dependent kinases (CDKs) have recently raised considerable attention because of their central role in the regulation of cell cycle progression. A high incidence of genetic mutation of CDK substrates and deregulaton of CDK modulators were found in a number of disease states,particularly in cancer. A novel serie...
Development of Enantioselective Fluorescent Sensors for Chiral Recognition

作者：Lin; Pu 刊期：2004年第Z1期

Novel chiral compounds have been synthesized for the enantioselective fluorescent recognition of alpha-hydroxycarboxylic acids and amino acids. By introducing dendritic branches to the chiral receptor units, the fluorescence signals of the receptors are significantly amplified because of the light-harvesting effect o...
Discovery of Potent, Selective and Reversible Caspase-3 Inhibitors

作者：Han; Yongxin; André; Giroux; John; Colucci; Christopher; I.; Bayly; Daniel; J.; Mckay; Sophie; Roy; Steve; Xanthoudakis; John; Vaillancourt; Dita; M.; Rasper; John; Tam; Paul; Tawa; Donald; W.; Nicholson; Robert; J.; Zamboni 刊期：2004年第Z1期

Recent studies towards understanding the molecular mechanisms of apoptosis have revealed the importance of a group of cysteinyl aspartate specific proteases, the caspases, in the programmed cell death process (Hengartner, M.O. Nature 2000, 407, 770). Caspase-3, in particular,has been characterized as the dominant eff...
Virtual Screening and Structure Generation Applied to Drug Design

作者：FAN; B.T.; CHEN; H.; F.; XIE; L.; YUAN; S.; G.; A.; PANAYE; J-P.; DOUCET 刊期：2004年第Z1期

The methods of computer-aided drug design can be divided into two categories according to whether or not the structures of receptors are known1, corresponding to two principal strategies:(1) searching the bio-active ligands against virtual combinatorial libraries and calculating the affinity energy between ligand and...
Proteomics and Its Application in Biomarker Discovery and Drug Development

作者：He; Qing-Yu; Chiu; Jen-Fu 刊期：2004年第Z1期

Proteomics is a research field aiming to characterize molecular and cellular dynamics in protein expression and function on a global level. The introduction of proteomics has been greatly broadening our view and accelerating our path in various medical researches. The most significant advantage of proteomics is its a...

合成材料行业发展

合成化学杂志统计源期刊

Chinese Journal of Synthetic Chemistry

Chemistry of 1,16-Dihydroxytetraphenylene and 2,3,9,10-Tetrakis(trimethylsilyl) pentacene

New Chiral Ligands: From Fundamental Research to Potential Industrial Applications

Studies on Atropo-Enantioselective Synthesis of the Natural Chiral Axial Biaryls

Approaches for Making High Performance Polymer Materials from Commodity Polymers

Skeletal Amorphous Nickel Based Alloy Catalysts and Magnetically Stabilized Bed Hydrogenation Technology

High Throughput and High Speed Organic Synthesis in Drug Discovery: An Integration of Chemistry and Technology

High Nonlinear Optic Activity Chromophore- Design and Synthesis

Novel Oxindoles as Potent Anti-HIV Agents

Pharmaceutical Industry Oriented Homogeneous Catalysis

Synthesis and Characterization of ZnO Nanowires

Bisarylmaleimides & the Corresponding Indolocarbazoles as Kinase Inhibitors

Development of Enantioselective Fluorescent Sensors for Chiral Recognition

Discovery of Potent, Selective and Reversible Caspase-3 Inhibitors

Virtual Screening and Structure Generation Applied to Drug Design

Proteomics and Its Application in Biomarker Discovery and Drug Development

中学化学教学参考

化学工程与装备

化学教育

中学化学

化学教与学

色谱

化学教学

中国农机化学报

分析化学

化学试剂

化学世界

化学研究与应用

合成化学杂志 统计源期刊

Chinese Journal of Synthetic Chemistry

Chemistry of 1,16-Dihydroxytetraphenylene and 2,3,9,10-Tetrakis(trimethylsilyl) pentacene

New Chiral Ligands: From Fundamental Research to Potential Industrial Applications

Studies on Atropo-Enantioselective Synthesis of the Natural Chiral Axial Biaryls

Approaches for Making High Performance Polymer Materials from Commodity Polymers

Skeletal Amorphous Nickel Based Alloy Catalysts and Magnetically Stabilized Bed Hydrogenation Technology

High Throughput and High Speed Organic Synthesis in Drug Discovery: An Integration of Chemistry and Technology

High Nonlinear Optic Activity Chromophore- Design and Synthesis

Novel Oxindoles as Potent Anti-HIV Agents

Pharmaceutical Industry Oriented Homogeneous Catalysis

Synthesis and Characterization of ZnO Nanowires

Bisarylmaleimides & the Corresponding Indolocarbazoles as Kinase Inhibitors

Development of Enantioselective Fluorescent Sensors for Chiral Recognition

Discovery of Potent, Selective and Reversible Caspase-3 Inhibitors

Virtual Screening and Structure Generation Applied to Drug Design

Proteomics and Its Application in Biomarker Discovery and Drug Development

中学化学教学参考

化学工程与装备

化学教育

中学化学

化学教与学

色谱

化学教学

中国农机化学报

分析化学

化学试剂

化学世界

化学研究与应用

合成化学杂志统计源期刊