摘要:目的探讨胶质细胞源性神经营养因子受体α1(GFRα-1)在儿童未成熟畸胎瘤发生、发展中的作用。方法34例畸胎瘤患儿根据病理结果分为未成熟畸胎瘤11例(观察组)与成熟畸胎瘤23例(对照组),采用实时荧光定量PCR法和Western blot法分别检测两组GFRα-1 mRNA和蛋白的表达水平。结果观察组GFRα-1 mRNA及蛋白表达水平均高于对照组,P均〈0.05。结论 GFRα-1在儿童未成熟畸胎瘤组织中高表达,可能成为区分儿童畸胎瘤良恶性的分子标志物。
注:因版权方要求,不能公开全文,如需全文,请咨询杂志社
热门期刊服务
Journal of Integrative Plant Biology Journal of Integrative Agriculture Journal of Beijing Institute of Technology Journal of Harbin Institute of Technology Journal of Wuhan University of Technology Journal of Meteorological Research Journal of Materials Science Technology World Journal of Gastroenterology Journal of Geographical Sciences Chinese Journal of Integrative Medicine Journal of Computer Science and Technology Journal of Tropical Meteorology