摘要:STAT3是STATs家族的重要成员,在多种恶性肿瘤中高表达,通过抑制细胞凋亡等机制促进肿瘤的发生和发展。本文综述了STAT3的结构、生物学特点、在人类常见恶性肿瘤中的表达及其意义的研究进展。
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