摘要：Objective To better understand the clinical featuresof human adenovirus type 7 (hAdV7) pneumonia and toidentify whether there is a variation in the genome of thestrain ( CHN/BeiJing /2018 ) isolated during the smallscaleepidemic. Methods Forty-two patients were diagnosedwith hAdV7 pneumonia between October 27th,2017 and February 28th,2018. They were all males withan average age of (21 ± 2) years. Demographic and clinicaldata were reviewed and analyzed in detail. The nucleicacid of the epidemic strain was extracted from abronchoalveolar lavage fluid sample. Whole genome sequencing(WGS ) was then performed and sequenceswere compared with other hAdV7 strains distributed globally.Phylogenetic tree analysis was conducted based onwhole genome sequences of the epidemic strain.

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