首页 期刊 中国医学文摘·耳鼻咽喉科学 Pathological classification and prognosis of renal damage caused by antineutrophil cytoplasmic antibody associated vasculitis 【正文】

Pathological classification and prognosis of renal damage caused by antineutrophil cytoplasmic antibody associated vasculitis

作者:费霞佩 Kidney; Disease; Center; 1st; Affil; Hosp; Coll; Med; Zhejiang; Univ; Hangzhou; 310003
aav   pathological   classification   prognosis   of  

摘要:Objective To analyze the pathological characteristicsand prognostic factors of antineutrophil cytoplasmicantibody (ANCA)-associated vasculitis (AAV). MethodsA retrospective analysis of AAV patients with renalbiopsy results admitted to Kidney Disease Center of theFirst Affiliated Hospital from January 2004 to February2017 was performed. The patients were divided into 4types according to Berden classification,and their clinical,pathological characteristics and prognosis were compared.The survival curves of each type of patients wereplotted by Kaplan-Meier method,and the difference ofsurvival curves was compared using Log-rank test. Withentering the maintenance dialysis as the endpoint,Coxregression was used to analyze the prognostic factors. ResultsA total of 175 patients with AAV,including 59 cases(33. 7%) of focal type,39 cases (22. 3%) of crescenttype,32 cases (18. 3%) of sclerosis type,45 cases(25. 7%) of mixed type.

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