摘要:前列腺癌是老年男性生殖系统一种常见的恶性肿瘤,是唯一最先发生骨转移而非内脏转移的实体肿瘤。因其具有很高的骨转移倾向,死于前列腺癌患者中约80%已发生骨转移。单核细胞趋化蛋白-1也称MCP-1或CCL-2属于趋化因子CC亚家族,其主要功能是趋化和激活单核细胞至炎症部位。近年来有学者提出MCP-1在前列腺癌骨转移过程中扮演重要角色。
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