摘要：目的 探讨静脉及鞘内联合用药加腰大池引流治疗颅脑手术后颅内感染的疗效.方法 选择34例符合条件的术后重症颅内感染患者,在全身及鞘内应用抗生素前提下行腰大池引流并评价其疗效.结果 引流10～54 d,平均21 d;鞘内注射5～16次,平均9次.34例患者颅内感染均痊愈,2例高龄患者颅内感染控制,其中1例死于严重肺部感染、肺功能衰竭,1例死于多脏器功能衰竭.32例存活患者随访1～6个月,无一例再次发生颅内感染.结论 静脉及鞘内联合用药加腰大池引流治疗重症颅内感染,疗效确切,能显著提高治愈率. Abstract： Objective To investigate the effect of lumbar continuous drainage in addition to intravenous and intrathecal administration in the treatment of the serious intracranial infection. Methods Thirty-four cases of postoperative serious intracranial infection were treated with lumbar continous drainage and intravenous and intrathecal admixture services, and the curative effects of the treatment were analysed. Results After 10 to 54 days of drainage, average 21 days, and 5-16 times intrathecal administration,average 9, the intracranial infection of all the 34 cases were cured, 2 advanced age cases died,one of lung complication,the other of MSOF(multiple system organ failure).The rest 32 cases without intracranial infection after 1-6 months follow-up. Conclusions The effect of lumbar continuous drainage in addition to intravenous and intrathecal administration in the treatment of the serious intracranial infection is determined,and the cure rate is increased.

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