摘要:目的观测胃癌患者血清中IFN-γ、IL-4和IL-6水平的变化,探讨其临床意义。方法采用ELISA法测定28例胃癌病人和36例正常人血清中三种细胞因子含量。结果胃癌病人血清中IFN-γ水平较正常人明显降低(P〈0.01),IL-4和IL-6水平较正常人明显增高(P〈0.01),其变化值与临床分期有关(P〈0.01)。结论胃癌病人机体免疫功能紊乱,血清中IFN-γ、IL-4和IL-6水平的变化与疾病的发生、发展有关。
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