摘要:目的研究不同交配方式SPF级Rncat先天性白内障小鼠繁殖学及晶状体浑浊度特征。方法以背景品种昆明小鼠为对照组,以Rncat先天性白内障小鼠近亲交配和最佳避免近交法交配为实验组,分别测定连续繁殖5代的繁殖性能及眼部晶状体浑浊度。结果与近亲交配的Rncat先天性白内障小鼠相比,最佳避免近交法交配的Rncat先天性白内障小鼠、昆明小鼠的繁殖性能、晶状体浑浊度差异显著(P〈0.05或P〈0.01)。结论近亲交配的Rncat先天性白内障小鼠和最佳避免近交法交配的Rncat先天性白内障小鼠繁殖性能和晶状体浑浊程度有一定差异,可以为实验人员提供参考。
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