摘要:Protein C为一种维生素k依赖性的血浆蛋白,常以无活性的酶原状态存在于血浆中.它可以由凝血酶(thrombin)激活为活性蛋白C(Activated Protein C),作用在内皮细胞上的Protein C通路的主要组成部分是:凝血酶、血栓调节蛋白、内皮细胞Protein C受体、Protein C及蛋白酶激活受体.活性ProteinC在缺血性缺氧、中风和感染反应中发挥着重要的作用,它可以抑制凝血,限制感染反应,有效的降低器官的损伤.
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