摘要:心肌素(Myocardin)通过与血清反应因子(SRF)结合成蛋白复合物,调节具有cArG-box基因的转录,主要介导心肌细胞及平滑肌细胞的分化。Myocardin表达与活性异常与许多心血管疾病密切关联。该文主要对Myocardin分子结构亚型、表达及活性调节的研究进展进行了综述。
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