摘要：类风湿关节炎（rheumatoid arthritis，RA）是一种侵犯全身多个关节，滑膜最先受累的结缔组织病，病程呈慢性、进行性、侵袭性，如果不及时治疗，病情可迅速进展，滑膜增生形成血管翳，逐渐破坏关节软骨和软骨下骨，终致关节强直、畸形和功能丧失，其中关节畸形是一种不可逆性的损害。
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