摘要:简介:大量研究表明,抑制HIV整合酶的活性是防止HIV-1传播的有效途径。含有咖啡酰基的化合物双咖啡酰奎尼酸(Dicaffeoylquinicacid)和L-巨菊酸(L chicoricacid)对HIV-1整合酶具有较高的抑制活性,其中咖啡酰基是药效团。
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